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All about myasthenia gravis causes of myasthenia gravis risk factors for myasthenia gravis thymus gland signs and symptoms of myasthenia gravis diagnosis of myasthenia gravis myasthenia gravis treatment myasthenic crisis myasthenia gravis and pregnancy prognosis of myasthenia gravis

What's a myasthenic crisis?

A myasthenic crisis occurs when weakness affects the muscles that control breathing. This can create a medical emergency requiring a respirator to help the person breathe or measures to prevent a person from taking in, or aspirating, too much air into their lungs. In individuals whose respiratory muscles are weak, infection, fever, a reaction to medication, or emotional stress can trigger a crisis. Plasma exchange may be performed to treat myasthenic crisis or to improve very weak patients before thymectomy. In this procedure, blood plasma is removed and replaced with purified plasma free of autoantibodies. It can produce a temporary improvement in symptoms, but is too expensive for long-term treatment. Another blood treatment, intravenous immunoglobulin therapy, is also used for myasthenic crisis. In this procedure, large quantities of purified immune proteins (immunoglobulins) are injected. For unknown reasons, this leads to symptomatic improvement in up to 85% of patients. It is also too expensive for long-term treatment.

More information on myasthenia gravis

What is myasthenia gravis? - Myasthenia gravis is a disorder of neuromuscular function due to the presence of antibodies to acetylcholine receptors at the neuromuscular junction.
What causes myasthenia gravis? - Myasthenia gravis is caused by a defect in the transmission of nerve impulses to muscles. Deficiency of acetylcholine at the neuromuscular junctions causes myasthenia gravis.
What're the risk factors for myasthenia gravis? - Myasthenia gravis commonly affects young adult women and older men. Myasthenia gravis may be associated with other autoimmune diseases.
What's the role of the thymus gland? - The thymus gland plays an important role in the development of the immune system in early life. In most adults with myasthenia gravis, the thymus gland is abnormal.
What're the signs and symptoms of myasthenia gravis? - Symptoms of myasthenia gravis include fatigue and exhaustion of the muscular system with a tendency to fluctuate in severity without sensory disturbance or atrophy.
How is myasthenia gravis diagnosed? - Myasthenia gravis is often diagnosed accurately by a careful medical history and a neuromuscular exam, but several tests are used to confirm the diagnosis.
What's the treatment for myasthenia gravis? - The treatment of myasthenia gravis depends on several factors, including age, overall health, severity of disease, and rate of disease progression.
What's a myasthenic crisis? - A myasthenic crisis occurs when weakness affects the muscles that control breathing. Plasma exchange may be performed to treat myasthenic crisis.
Does myasthenia gravis affect pregnancy? - Pregnant women with myasthenia gravis often have more weakness and fatigue because of the added weight and effort of pregnancy.
What's the prognosis of myasthenia gravis? - Myasthenia gravis is a chronic disease. With treatment, patients with myasthenia gravis will have significant improvement of their muscle weakness.
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