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All about Guillain-Barre syndrome causes of Guillain-Barre syndrome symptoms of Guillain-Barre syndrome diagnosis of Guillain-Barre syndrome treatment for Guillain-Barre syndrome Miller fisher syndrome

What's Miller fisher syndrome?

Miller fisher syndrome (MFS) is a variant of Guillain-Barre syndrome characterized by the triad of ophthalmoplegia, ataxia and areflexia. Miller Fisher syndrome is a syndrome of acute external ophthalmoplegia, ataxia and areflexia without significant motor or sensory deficit in the limbs and usually results in complete recovery without specific treatment. It's

accurate anatomic lesion sites and pathogeneiss is still unknown.

Unlike GBS, MFS causes descending paralysis, i.e. paralysis that begins in the upper body and gradually spreads downward. The difference between MFS and GBS is that different nerve groups are affected such that paralysis in GBS tends to start in the legs and move up, where in MFS it starts in the head, affecting eye muscles, balance and slowly descends to the neck arms etc. MFS does not generally have the life threatening aspects of GBS but can be very difficult to live through with double vision, nausea, weakness, difficulty.

Like Guillain-Barré syndrome, symptoms may be preceded by a viral illness. Additional symptoms include generalized muscle weakness and respiratory failure. The majority of individuals with Miller Fisher syndrome have a unique antibody that characterizes the disorder. A spinal tap reveals the presence of elevated protein levels. The patient experiences the classical triad of ataxia, opthalmoplegia and areflexia: loss of tendon reflexes and coordination, difficulty walking and standing, vision problems. Also tingling, numbness, dizziness, nausea. Anti-GQ1b antibodies are produced.

Treatment for Miller Fisher syndrome is identical to treatment for Guillain-Barré syndrome: intravenous immunoglobulin (IVIg) or plasmapheresis (a procedure in which antibodies are removed from the blood) and supportive care.

More information on Guillain-Barre syndrome

What is Guillain-Barre syndrome? - Guillain-Barre syndrome is a neurological disorder in which the body's immune system attacks part of the peripheral nervous system.
What causes Guillain-Barre syndrome? - The causes of Guillain Barre syndrome are unknown. The cause and course of Guillain-Barre syndrome is an active area of neurological investigation.
What are symptoms of Guillain-Barre syndrome? - Symptoms of Guillain-Barre syndrome vary, the first prominent symptom is weakness. The weakness is accompanied by paresthesia.
How is Guillain-Barre syndrome diagnosed? - Guillain-Barre syndrome can be difficult to diagnose in its earliest stages. Nerve conduction velocity (NCV) test can help the diagnosis.
What's the treatment for Guillain-Barre syndrome? - The goal of the treatment for Guillain-Barre syndrome is to lessen the severity of the illness and to assist in the recovery.
What's Miller fisher syndrome? - Miller fisher syndrome (MFS) is a variant of Guillain-Barre syndrome characterized by the triad of ophthalmoplegia, ataxia and areflexia.
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