What's the treatment for Lambert-Eaton Myasthenic syndrome?
There is no cure for LEMS. However, multiple treatment options are available to improve symptoms and sometimes produce remission. Symptomatic treatment consists of 3,4-diaminopyridine (3,4-DAP). LEMS has been treated with pyridostigmine bromide (Mestinon) to increase the transmission of acetylcholine across the neuromuscular junction, a drug called diaminopyridine (DAP) and immunosuppressants (the steroid prednisone, azathioprine, cyclosporine). Plasma exchange provides improvement in some patients with LEMS, as may intravenous immunoglobulin (IVIg). Patients over 50 with a history of long-term smoking are most likely to have an associated tumor. If the tumor is cured, the LEMS may vanish. |
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