health care  
All about Huntington's disease causes of Huntington's disease Huntington's disease symptoms diagnosis of Huntington's disease treatment for Huntington's disease

How is Huntington's disease diagnosed?

Someone with a family history of Huntington's disease who begins to have symptoms often is diagnosed based on a physical and neurological exam. A blood test is now available to detect the presence of the genetic abnormality that causes Huntington's disease. Everyone who carries the Huntington's disease gene eventually will develop the disease,

but the test cannot predict when symptoms will begin.

A genetic test is available for confirmation of the clinical diagnosis. In this test, a small blood sample is taken, and DNA from it is analyzed to determine the CAG repeat number. A person with a repeat number of 30 or below will not develop Huntington's disease. A person with a repeat number between 35 and 40 may not develop the disease within their normal lifespan. A person with a very high number of repeats (70 or above) is likely to develop the juvenile-onset form.

Prenatal testing is available. A person at risk for Huntington's disease (a child of an affected person) may obtain fetal testing without determining whether she herself carries the gene. This "nondisclosing" test, also called a linkage test, examines the pattern of DNA near the gene in both parent and fetus, but does not analyze for the triple repeat itself. If the DNA patterns do not match, the fetus can be assumed not to have inherited the HD gene, even if present in the parent. A pattern match indicates the fetus probably has the same genetic makeup of the at-risk parent. It does not indicate whether the parent (or fetus) actually has the defective gene.


More information on Huntington's disease

What is Huntington's disease? - Huntington's disease (HD) is a hereditary neurological disorder characterized by movement, cognitive, and psychiatric symptoms.
What causes Huntington's disease? - Huntington's disease is caused by an inherited dominant gene mutation on chromosome 4. Huntington's disease is a progressive disorder.
What're the symptoms of Huntington's disease? - Huntington's disease is characterized by progressive mental and physical deterioration. Early symptoms of Huntington's disease may affect cognitive ability.
How is Huntington's disease diagnosed? - Patient with a family history of Huntington's disease who begins to have symptoms is diagnosed based on a physical and neurological exam.
What's the treatment for Huntington's disease? - There is no cure for Huntington's disease. Treatment is aimed at slowing progression and maximizing ability to function for as long as possible.
Neurological disorders Mainpage

Topics in neurological disorders

Autoimmune nervous system diseases
Autonomic nervous system diseases
Degenerative nervous system diseases
Central nervous system diseases
Brain diseases
Cranial nerve disorders
Language disorders
Perceptual disorders
Motor neuron diseases
Neurologic manifestations
Movement disorders
Peripheral nerve disorders
Sleep disorders
Spinal cord diseases

Featured neurological articles

Multiple sclerosis
Cerebral palsy
Migraine headache
Cluster headache
Alzheimer's disease
Chronic fatigue syndrome
Parkinson's disease
Carpal tunnel syndrome
Peripheral neuropathy
Diabetic neuropathy
Lower back pain
Sleep apnea
Brain tumor
Brain cancer
Spinal cord tumors

Nutrition for neurological disorders

MindSoothe for emotional health
MindSoothe, a natural herbal remedy, contains a selection of herbs known for their calming and supportive function in maintaining brain and nervous system health, emotional balance and overall wellbeing.

Neuro Natural Memory
Specifically formulated to help support brain health, Neuro-Natural Memory may help improve memory, concentration levels and reduce the potential for brain and memory function problems.

Triple Complex Sleep Tonic
Sleep Tonic helps the body relax and produce all the hormones essential for healthy sleep; safe for everyone, including pregnant and nursing women, children, and small babies.

All information is intended for reference only. Please consult your physician for accurate medical advices and treatment. Copyright 2005,, all rights reserved. Last update: July 18, 2005