What is Huntington's chorea?
Huntington's chorea (Huntington's disease) is a dominantly inherited disease typified by choreoathetosis, rigidity, dementia, ataxia, and ophthalmoplegia. A chorea is a disorder of the nervous system that causes uncontrollable and irregular muscle movements, especially of the arms, legs, and face.
Symptoms of Huntington's chorea usually develop between 35 and 40 years of age. The risk of developing Huntington’s chorea decreases rapidly after age 50 for each year that passes without developing the disease. The affected portions of the brain decay slowly. This leads to increasing chorea and loss of mental abilities. Eventually, abnormal movements and dementia become so severe that the person can no longer care for his or her self.
Huntington's Chorea is a progressive degenerative disease characterized by a wide-based, bouncy gait, abnormal speech patterns, jerky movements of the limbs, body, and face. It is also associated with personality changes and can start abruptly as deterioration in mental state. The onset is usually gradual and slow to notice, facial movements and involuntary movements progress and can be very disabling.