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All about amyotrophic lateral sclerosis (ALS) types of amyotrophic lateral sclerosis causes of amyotrophic lateral sclerosis symptoms of amyotrophic lateral sclerosis diagnosis of amyotrophic lateral sclerosis treatment for amyotrophic lateral sclerosis

What types of amyotrophic lateral sclerosis are there?

Two major types of amyotrophic lateral sclerosis are known: familial and sporadic. Familial amyotrophic lateral sclerosis accounts for about 10% of all ALS cases. As the name suggests, familial ALS is believed to be caused by the inheritance of one or more faulty genes. About 15% of families with this type of ALS have mutations in the gene for SOD-1. SOD-1 gene defects are dominant, meaning only one gene copy is needed to develop the disease. Therefore, a parent with the faulty

gene has a 50% chance of passing the gene along to a child.

Sporadic amyotrophic lateral sclerosis has no known cause. While many environmental toxins have been suggested as causes, to date no research has confirmed any of the candidates investigated, including aluminum and metal dental fillings. As research progresses, it is likely that many cases of sporadic ALS will be shown to have a genetic basis as well.

A third type, called Western Pacific amyotrophic lateral sclerosis, occurs in Guam and other Pacific islands. This form combines symptoms of both ALS and Parkinson's disease.

More information on amyotrophic lateral sclerosis (ALS)

What is amyotrophic lateral sclerosis? - Amyotrophic lateral sclerosis (ALS) is a progressive wasting away of certain nerve cells of the brain and spinal column called motor neurons.
What types of amyotrophic lateral sclerosis are there? - Two major types of amyotrophic lateral sclerosis are known: familial and sporadic. Familial amyotrophic lateral sclerosis accounts for about 10% of all ALS cases.
What causes amyotrophic lateral sclerosis? - The symptoms of amyotrophic lateral sclerosis are caused by the death of motor neurons in the spinal cord and brain.
What're the symptoms of amyotrophic lateral sclerosis? - Initial symptoms of amyotrophic lateral sclerosis include slight weakness in one leg, one hand, the face, or the tongue.
How is amyotrophic lateral sclerosis diagnosed? - The diagnosis of amyotrophic lateral sclerosis begins with a complete medical history and physical exam, plus a neurological exam.
What's the treatment for amyotrophic lateral sclerosis? - There is no cure for amyotrophic lateral sclerosis (ALS). Treatment focuses on keeping the person as strong and independent as possible.
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