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All about Wernicke-Korsakoff syndrome causes of Wernicke-Korsakoff syndrome symptoms of Wernicke-Korsakoff syndrome diagnosis of Wernicke-Korsakoff syndrome treatment for Wernicke-Korsakoff syndrome

What is Wernicke-Korsakoff syndrome?

Wernicke-Korsakoff syndrome (WKS) is a neurological disorder. Wernicke's Encephalopathy and Korsakoff's Psychosis are the acute and chronic phases, respectively, of the same disease. Wernicke-Korsakoff syndrome is a combination of

Korsakoff's syndrome which constitutes confusion, aphonia and confabulation and Wernicke's encephalopathy which is nystagmus, opthalmoplegia, coma and, if untreated, death. It is also known as cerebral beriberi, which is beriberi (thiamine deficiency disease) in the brain. This results from severe acute deficiency of thiamine superimposed on a chronic deficiency. Usually found in malnourished chronic alcoholics.

Korsakoff's syndrome, with symptoms of severe anterograde and retrograde amnesia, is caused by damage to mammillary bodies and other brain regions due to deficiency of thiamine. This is most often caused by chronic alcoholism, though other conditions including severe malnutrition, have been known to cause it. An association of Gayet-Wernicke and Korsakoff' syndromes frequently observed in alcoholic, nutritionally deficient patients with the Gayet-Wernicke syndrome. Patients develop symptoms of the Korsakoff syndrome, mainly amnesia with a tendency to confabulate with or without polyneuropathy.

More information on Wernicke-Korsakoff syndrome

What is Wernicke-Korsakoff syndrome? - Wernicke-Korsakoff syndrome (WKS) is a neurological disorder. Wernicke-Korsakoff syndrome is a combination of Korsakoff's syndrome and Wernicke's encephalopathy.
What causes Wernicke-Korsakoff syndrome? - Wernicke-Korsakoff syndrome is caused by a deficiency in the B vitamin thiamine. Thiamine plays a role in metabolizing glucose to produce energy for the brain.
What're the symptoms of Wernicke-Korsakoff syndrome? - Symptoms of Wernicke-Korsakoff syndrome include amnesia, confabulation, attention deficit, disorientation, and vision impairment.
How is Wernicke-Korsakoff syndrome diagnosed? - The diagnosis of Wernicke-Korsakoff syndrome can be confirmed by measuring blood levels of thiamine. Examination of the nervous/muscular system may show polyneuropathy.
What's the treatment for Wernicke-Korsakoff syndrome? - The goals of treatment of Wernicke-Korsakoff syndrome are to control symptoms as much as possible and to prevent progression of the disorder.
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